| Título: | Actinide Dependent Shadow Biosphere of Archaea and Viroids and Hemispheric Dominance |
| Autores: |
Kurup A., Ravikumar; Professor of Metabolic Medicine and Neurology
The Metabolic Disorders Research Centre, TC 4/1525, Gouri Sadan, Kattu Road, North of Cliff House, Kowdiar PO, Trivandrum, Kerala, India Kurup, Parameswara Achutha; Professor of Metabolic Medicine and Neurology The Metabolic Disorders Research Centre, TC 4/1525, Gouri Sadan, Kattu Road, North of Cliff House, Kowdiar PO, Trivandrum, Kerala, India |
| Fecha: | 2011-12-31 |
| Publicador: | Advances in Natural Science |
| Fuente: |
 |
| Tipo: |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article |
| Tema: |
Archaea; Viroids; Cholesterol; Digoxin; Hemispheric dominance |
| Descripción: | ObjectiveEndogenous digoxin has been related to hemispheric dominance. The possibility of endogenous digoxin synthesis by actinide based primitive organism like archaea with a mevalonate pathway and cholesterol catabolism was considered. Methods10 normal individuals each of right handed and left hemispheric dominant group, left handed and right hemispheric dominant group and amphidextrous and bihemispheric dominant individuals were included in the study. Cholesterol substrate was added to the plasma of the patients and the generation of cytochrome F420, free RNA, free DNA, polycyclic aromatic hydrocarbon, hydrogen peroxide, serotonin, pyruvate, ammonia, glutamate, cytochrome C, hexokinase, ATP synthase, HMG CoA reductase, digoxin and bile acids were studied. The changes with the addition of antibiotics and rutile to the patient’s plasma were also studied. ResultsThe plasma of the bihemispheric dominant group showed detectable levels of the above mentioned parameters after incubation for 1 hour and addition of cholesterol substrate resulted in still further increase in these parameters. The addition of antibiotics to the bihemispheric dominant group caused a decrease in all the parameters while addition of rutile increased their levels. The plasma of right hemispheric dominant group showed a significant increase in the above mentioned parameters as compared to bihemispheric dominance group. The addition of antibiotics to the right hemispheric dominant group caused a decrease in all the parameters while addition of rutile increased their levels but the extent of change was more in right hemispheric dominant group as compared to bihemispheric dominant group. The addition of antibiotics to the left hemispheric dominant group caused a decrease in all the parameters while addition of rutile increased their levels but the extent of change was less in left hemispheric dominant group as compared to bihemispheric dominant group. ConclusionAn actinide dependent shadow biosphere of intracellular archaea and viroids constitutes the third element regulating hemispheric dominance.Key words: Archaea; Viroids; Cholesterol; Digoxin; Hemispheric dominance |
| Idioma: | Inglés |
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