| Título: | ORAL VERSUS NASAL VASOPRESSIN IN THE TREATMENT OF NOCTURNAL ENURESIS IN 5- TO 12-YEAR-OLD CHILDREN |
| Autores: |
TAGHAVI ARDAKANI, Abbas; MD,Assistant Professor of Pediatrics,Department of Pediatrics, Kashan University of Medical Sciences, Kashan, Iran HONARPISHEH, Ali; MD,Associate Professor of Pediatrics,Department of Pediatrics, Kashan University of Medical Sciences, Kashan, Iran FAKHARIAN, Esmaeil; MD, Associate Professor of Neurosurgery,Department of Neurosurgery, Kashan University of Medical Sciences, Kashan, Iran TALEBIAN, Ahmad; MD<Professor of pediatrics, Department of Pediatrics, Kashan University of Medical Sciences, Kashan, Iran MOOSAVI, Gholam Abbas; Master of Science, Department of public health, Kashan University of Medical Sciences,Kashan, Iran SADAT, Zohreh; Master of Science, Department of Nursing,Kashan University of Medical Sciences,Kashan, Iran HONARPISHEH, Parisa; MD,General practitioner, Kashan University of Medical Sciences, Kashan, Iran |
| Fecha: | 2010-07-19 |
| Publicador: | Iranian Journal of Child Neurology |
| Fuente: |
 |
| Tipo: |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion original articles |
| Tema: | No aplica |
| Descripción: | ObjectiveNocturnal enuresis is a common childhood problem and has various treatments.This study was carried out to compare oral and nasal vasopressin in the treatment of nocturnal enuresis in 5- to 12-year-old children who were referred to the Shahid Beheshti Clinic in 2008.Materials & MethodsThis study included 100 children (62 males and 38 females) with nocturnal enuresis. One group (50 patients) received 20 mcg nasal vasopressin which increased up to 40 mcg, depending on the patients' response. The other group (50 patients) received 0.2 mg oral vasopressin which increased up to 0.4 mg.The patients were followed up for one month after response to the last dose of drug. Data were recorded in prepared forms and analyzed using Chi-Square and Fisher Test.ResultsThe success rate with oral and nasal method was 80% and 92%, respectively (P=0.08). Only 2% of the children had complications during the treatment; one child treated orally developed gastroenteritis and another child treated with the nasal method developed convulsions (P=1). Sixteen percent of the children treated with the oral method and 28% of the children treated with the nasal method had recurrence (P=0.148).ConclusionOral and nasal forms of vasopressin have equal therapeutic effects. However, oral form of the treatment has fewer serious side effects and is easier to use. Therefore, the use of oral medicine is recommended.Keywords:Nasal vasopressin, Nocturnal enuresis, Oral vasopressin |
| Idioma: | Inglés |
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