| Título: | Impacts of fresh lime juice and peel on atherosclerosis progression in an animal model |
| Autores: |
Boshtam, Maryam; Isfahan Cardiovascular Research Center, Isfahan Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran Asgary, Sedigheh; Professor, Apply Physiology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran Moshtaghian, Jamal; Assistant Professor, Department of Sciences, University of Isfahan, Isfahan, Iran Naderi, Gholamali; Associate Professor, Isfahan Cardiovascular Research Center, Isfahan Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran Jafari, Narges; Assistant Professor, Islamic Azad University, Falavarjan Branch, Isfahan, Iran Sobhan, Ahmad; Professor, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran |
| Fecha: | 2013-11-15 |
| Publicador: | ARYA Atheroscler |
| Fuente: |
Ver documento |
| Tipo: | |
| Tema: | No aplica |
| Descripción: | BACKGROUND: The main protective role of antioxidants in the progression of atherosclerosis has been shown in some studies. Therefore, this project evaluated the effects of Citrus aurantiifolia (Christm) juice and peel on antioxidant activity and atherosclerosis progression in rabbits receiving a hypercholesterolemic diet. METHODS: Forty white New Zealand male rabbits were randomly allocated to four groups. All groups were on hypercholesterolemic diet for two months. While the first group was considered as the hypercholesterolemic control, groups 2 and 3 (intervention groups) received 5 ml/day lime juice and 1 g/day dried lime peel powder, respectively. Group 4 was fed a normal diet (normal control). Before and after the study, weight was measured and a fasting blood specimen was taken from the rabbits. Serum lipids analyses and antioxidant activity evaluations were then performed. The rabbits’ aorta and coronary arteries were separated and the presence of fatty streak was studied. RESULTS: Comparing to the hypercholesterolemic control group (-25.2 ± 7.0), only the plasma total antioxidant capacity change was significantly more in rabbits supplemented with lime juice (16.3 ± 14.7) and peel (8.6 ± 7.1), (P = 0.008). The presence of fatty streaks in coronary arteries and aorta of the intervention groups [juice (0.2 ± 0.01); peel (0.0 ± 0.00)] was significantly decreased compared to the hypercholesterolemic control group (1.2 ± 0.4) (P < 0.001). CONCLUSION: Based on our findings, Citrus aurantiifolia peel and juice increase plasma antioxidant capacity in rabbits, and can thus prevent or decelerate the process of atherogenesis. However, lime peel is more effective than lime juice. KEYWORDS: Animal Study, Atherosclerosis, Fatty Streak, Hypercholesterolemic Diet, Intervention, Juice, Lime, Peel |
| Idioma: | Inglés |
1 COMPARING THE EFFECTS OF LOVASTATIN AND CORNUS MAS FRUIT ON FIBRINOGEN LEVEL IN HYPERCHOLESTEROLEMIC RABBITS por Asgary, Sedigheh; Associate Professor of Pharmacognosy, Isfahan Cardiovascular Research Center, Applied Physiology Research Center, Isfahan University of Medical Sciences, Isfahan,Rafieian-Kopaei, Mahmoud; Professor of Pharmacology, Shahrekord Medicinal Plants Research Center, Shahrekord University of Medical Sciences, Sharekord,Adelnia, Azadeh; MSc, Animal Physiology, Department of Biology, University of Payam-Noor. Isfahan,Kazemi, Somayeh; MSc, Animal Physiology, Department of Biology, The University of Isfahan, Isfahan,Shamsi, Fatemeh; MSc, Animal Physiology, Department of Biology, University of Payam-Noor. Isfahan | 6 IS THERE ANY RELATIONSHIP BETWEEN C-REACTIVE PROTEIN LEV-EL AND COMPLEX CORONARY PLAQUES IN PATIENTS WITH UNSTABLE ANGINA? por Sadeghi, Masoumeh; Associate Professor, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,,Pourmoghaddas, Masoud; Professor, Isfahan University of Medical Sciences, Isfahan,Tavasoli, Aliakbar; Associate Professor, Isfahan University of Medical Sciences, Isfahan,Roohafza, Hamidreza; Psychiatrist, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan |
2 THE RELATIONSHIP BETWEEN ANKLE-BRACHIAL INDEX AND NUM-BER OF INVOLVED CORONARIES IN PATIENTS WITH STABLE ANGINA por Sadeghi, Masoumeh; Associated Professor of Cardiology, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,,Tavasoli, AliAkbar; Associated Professor of Cardiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan,Roohafza, Hamidreza; Psychiatrist of Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Sarrafzadegan, Nizal; Professor of Cardiology, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan | 7 DELAY AND ITS RELATED FACTORS IN SEEKING TREATMENT IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION por Taghaddosi, Mohsen; Department of Medical-Surgical Nursing, Kashan University of Medical Sciences, Kashan,Dianati, Mansour; Medical Student, Kashan University of Medical Sciences, Kashan,Fath Gharib Bidgoli, Javad; Department of Medical Technology, Kashan University of Medical Sciences, Kashan,Bahonaran, Javad; Department of Medical Technology, Kashan University of Medical Sciences, Kashan |
3 LIVER-PROTECTIVE EFFECTS OF HYDROALCOHOLIC EXTRACT OF ALLIUM HIRTIFOLIUM BOISS. IN RATS WITH ALLOXAN-INDUCED DI-ABETES MELLITUS por Kazemi, Somayeh; Department of Biology, School of Sciences, The University of Isfahan and Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Asgary, Sedigheh; Isfahan Cardiovascular Research Center, Applied Physiology Research Center, Isfahan University of Medical Sciences, Isfahan,Moshtaghian, Jamal; Department of Biology, School of Sciences, The University of Isfahan, Isfahan,Rafieian, Mahmoud; Medicinal Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord,Adelnia, Azadeh; Department of Biology, School of Science, Isfahan Payam-e-Noor University, Isfahan,Shamsi, Fatemeh; Department of Biology, School of Science, Isfahan Payam-e-Noor University, Isfahan | 8 PULMONIC VALVE ENDOCARDITIS WITH PULMONARY ARTERY ENDARTERITIS IN A YOUNG MAN WITH CONGENITAL VENTRAL SEPTAL DEFECT por Fazlinezhad, Afsoon; Associate Professor of Cardiology, Department of Echocardiography, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad,Fallah, Azadeh; Resident of Cardiology, Department of Cardiology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad,Esfahanizadeh, Jamil; Assistant Professor of Cardiac Surgery, Department of Cardiac Surgery, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, |
4 EFFECT OF HYDROGENATED, LIQUID AND GHEE OILS ON SERUM LI-PIDS PROFILE por Mohammadifard, Noushin; MSc, Department of Nutrition, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Nazem, Masoud; Associate Professor, Department of Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan,Naderi, Gholam-Ali; Associate Professor, Department of Basic Sciences, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Saghafian, Faezeh; BSc, Department of Nutrition, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Sajjadi, Firoozeh; BSc, Department of Nutrition, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Maghroon, Maryam; BSc, Department of Nutrition, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Bahonar, Ahmad; MD, MPH, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Alikhasi, Hasan; BSc, Department of Nutrition, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Nouri, Fatemeh; Biostatistics Unit, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan | 9 EFFECT OF DIFFERENT PHYSICAL ACTIVITY TRAINING METHODS ON OVERWEIGHT ADOLESCENTS por Ghatrehsamani, Shohreh; Research Assistant, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Khavarian, Noushin; Research Assistant, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Beizaei, Maryam; Research Assistant, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Ramedan, Reza; Senior Expert, Isfahan Sport Training Organization, Isfahan,Poursafa, Parinaz; Senior Expert, Isfahan Sport Training Organization, Isfahan,Kelishadi, Roya; Associate Professor of Pediatrics, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan |
5 THE ASSOCIATION OF GENERAL AND CENTRAL OBESITY WITH MA-JOR DIETARY PATTERNS IN ADULT WOMEN LIVING IN TEHRAN, IRAN por Rezazadeh, Arezoo; MSc, Department of Community Nutrition, School of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran,Rashidkhani, Bahram; PhD, Department of Community Nutrition, School of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran | 10 EVALUATION OF LEPTIN AND ADIPONECTIN LEVELS IN PATIENTS WITH STABLE ANGINA PECTORIS por Mozafari, Masoud; Cardiology Resident, Isfahan University of Medical Sciences, Isfahan,Sadeghi, Masoumeh; Associate Professor of Cardiology, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Sanei, Hamid; Associate Professor of Cardiology, Isfahan University of Medical Sciences, Isfahan,Ramezani, Mohammad Arash; Community Medicine Specialist, Isfahan Cardiovascular Research Center, Isfahan,Golabchi, Allahyar; Cardiology Resident, Isfahan University of Medical Sciences, Isfahan,Sarrafzadegan, Nizal; Professor of Cardiology, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences Isfahan |