| Título: | Amiodarone versus lidocaine for the prevention of reperfusion ventricular fibrillation: A randomized clinical trial |
| Autores: |
Ghavidel, Alireza; Associate Professor, Heart Valve Disease Research Center AND Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran Nabavi, Salaheddin; Cardiac Surgery Fellow, Heart Valve Disease Research Center AND Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran Haghjoo, Majid; Associate Professor, Cardiac Electrophysiology Research Center AND Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran Toutonchi, Zia; Associate Professor, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran Mirmesdagh, Yalda; Research Fellow, Heart Valve Disease Research Center AND Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran Javadikasgari, Hoda; Research Fellow, Heart Valve Disease Research Center AND Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran |
| Fecha: | 2013-11-15 |
| Publicador: | ARYA Atheroscler |
| Fuente: |
Ver documento |
| Tipo: | |
| Tema: | No aplica |
| Descripción: | BACKGROUND: Reperfusion ventricular fibrillation after aortic cross clamp is one of the important complications of open cardiac surgery and its prevention could reduce myocardial injuries. This study aimed to evaluate the efficacy of single dose of amiodarone or lidocaine by the way of pump circuit three minutes before aortic cross clamp release and compared the results with normal saline as placebo in a randomized double blinded controlled trial. METHODS: One hundred fifty patients scheduled for first time elective coronary artery bypass graft surgery were randomly assigned to receive either single dose of amiodarone (150 mg), lidocaine (100 mg), or normal saline (5 ml) three minutes before aortic cross clamp release. The incidence of ventricular fibrillation and the need for reuse of drug were compared between these groups by chi-square, Student’s t-test, Mann-Whitney test, and One-way ANOVA. SPSS software was used for statistical analysis. RESULTS: The incidence of ventricular fibrillation is higher in the placebo group (15.9%) compare to lidocaine (11.8%) and amiodarone (8.9%) groups; however, there was no statistical difference among the three groups (P = 0.41). Moreover, the reuse of amiodarone (22.7%) was statistically higher (P < 0.05) than lidocaine (5.9%). CONCLUSION: This study showed no difference among lidocaine, amiodarone, and placebo in preventing ventricular fibrillation after aortic cross clamp release. KEYWORDS: Amiodarone, Lidocaine, Ischemia Reperfusion Injury, Ventricular Fibrilation, Randomized Controlled Trial |
| Idioma: | Inglés |
1 COMPARING THE EFFECTS OF LOVASTATIN AND CORNUS MAS FRUIT ON FIBRINOGEN LEVEL IN HYPERCHOLESTEROLEMIC RABBITS por Asgary, Sedigheh; Associate Professor of Pharmacognosy, Isfahan Cardiovascular Research Center, Applied Physiology Research Center, Isfahan University of Medical Sciences, Isfahan,Rafieian-Kopaei, Mahmoud; Professor of Pharmacology, Shahrekord Medicinal Plants Research Center, Shahrekord University of Medical Sciences, Sharekord,Adelnia, Azadeh; MSc, Animal Physiology, Department of Biology, University of Payam-Noor. Isfahan,Kazemi, Somayeh; MSc, Animal Physiology, Department of Biology, The University of Isfahan, Isfahan,Shamsi, Fatemeh; MSc, Animal Physiology, Department of Biology, University of Payam-Noor. Isfahan | 6 IS THERE ANY RELATIONSHIP BETWEEN C-REACTIVE PROTEIN LEV-EL AND COMPLEX CORONARY PLAQUES IN PATIENTS WITH UNSTABLE ANGINA? por Sadeghi, Masoumeh; Associate Professor, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,,Pourmoghaddas, Masoud; Professor, Isfahan University of Medical Sciences, Isfahan,Tavasoli, Aliakbar; Associate Professor, Isfahan University of Medical Sciences, Isfahan,Roohafza, Hamidreza; Psychiatrist, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan |
2 THE RELATIONSHIP BETWEEN ANKLE-BRACHIAL INDEX AND NUM-BER OF INVOLVED CORONARIES IN PATIENTS WITH STABLE ANGINA por Sadeghi, Masoumeh; Associated Professor of Cardiology, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,,Tavasoli, AliAkbar; Associated Professor of Cardiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan,Roohafza, Hamidreza; Psychiatrist of Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Sarrafzadegan, Nizal; Professor of Cardiology, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan | 7 DELAY AND ITS RELATED FACTORS IN SEEKING TREATMENT IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION por Taghaddosi, Mohsen; Department of Medical-Surgical Nursing, Kashan University of Medical Sciences, Kashan,Dianati, Mansour; Medical Student, Kashan University of Medical Sciences, Kashan,Fath Gharib Bidgoli, Javad; Department of Medical Technology, Kashan University of Medical Sciences, Kashan,Bahonaran, Javad; Department of Medical Technology, Kashan University of Medical Sciences, Kashan |
3 LIVER-PROTECTIVE EFFECTS OF HYDROALCOHOLIC EXTRACT OF ALLIUM HIRTIFOLIUM BOISS. IN RATS WITH ALLOXAN-INDUCED DI-ABETES MELLITUS por Kazemi, Somayeh; Department of Biology, School of Sciences, The University of Isfahan and Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Asgary, Sedigheh; Isfahan Cardiovascular Research Center, Applied Physiology Research Center, Isfahan University of Medical Sciences, Isfahan,Moshtaghian, Jamal; Department of Biology, School of Sciences, The University of Isfahan, Isfahan,Rafieian, Mahmoud; Medicinal Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord,Adelnia, Azadeh; Department of Biology, School of Science, Isfahan Payam-e-Noor University, Isfahan,Shamsi, Fatemeh; Department of Biology, School of Science, Isfahan Payam-e-Noor University, Isfahan | 8 PULMONIC VALVE ENDOCARDITIS WITH PULMONARY ARTERY ENDARTERITIS IN A YOUNG MAN WITH CONGENITAL VENTRAL SEPTAL DEFECT por Fazlinezhad, Afsoon; Associate Professor of Cardiology, Department of Echocardiography, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad,Fallah, Azadeh; Resident of Cardiology, Department of Cardiology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad,Esfahanizadeh, Jamil; Assistant Professor of Cardiac Surgery, Department of Cardiac Surgery, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, |
4 EFFECT OF HYDROGENATED, LIQUID AND GHEE OILS ON SERUM LI-PIDS PROFILE por Mohammadifard, Noushin; MSc, Department of Nutrition, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Nazem, Masoud; Associate Professor, Department of Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan,Naderi, Gholam-Ali; Associate Professor, Department of Basic Sciences, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Saghafian, Faezeh; BSc, Department of Nutrition, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Sajjadi, Firoozeh; BSc, Department of Nutrition, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Maghroon, Maryam; BSc, Department of Nutrition, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Bahonar, Ahmad; MD, MPH, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Alikhasi, Hasan; BSc, Department of Nutrition, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Nouri, Fatemeh; Biostatistics Unit, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan | 9 EFFECT OF DIFFERENT PHYSICAL ACTIVITY TRAINING METHODS ON OVERWEIGHT ADOLESCENTS por Ghatrehsamani, Shohreh; Research Assistant, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Khavarian, Noushin; Research Assistant, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Beizaei, Maryam; Research Assistant, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Ramedan, Reza; Senior Expert, Isfahan Sport Training Organization, Isfahan,Poursafa, Parinaz; Senior Expert, Isfahan Sport Training Organization, Isfahan,Kelishadi, Roya; Associate Professor of Pediatrics, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan |
5 THE ASSOCIATION OF GENERAL AND CENTRAL OBESITY WITH MA-JOR DIETARY PATTERNS IN ADULT WOMEN LIVING IN TEHRAN, IRAN por Rezazadeh, Arezoo; MSc, Department of Community Nutrition, School of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran,Rashidkhani, Bahram; PhD, Department of Community Nutrition, School of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran | 10 EVALUATION OF LEPTIN AND ADIPONECTIN LEVELS IN PATIENTS WITH STABLE ANGINA PECTORIS por Mozafari, Masoud; Cardiology Resident, Isfahan University of Medical Sciences, Isfahan,Sadeghi, Masoumeh; Associate Professor of Cardiology, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Sanei, Hamid; Associate Professor of Cardiology, Isfahan University of Medical Sciences, Isfahan,Ramezani, Mohammad Arash; Community Medicine Specialist, Isfahan Cardiovascular Research Center, Isfahan,Golabchi, Allahyar; Cardiology Resident, Isfahan University of Medical Sciences, Isfahan,Sarrafzadegan, Nizal; Professor of Cardiology, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences Isfahan |