| Título: | RELATIONSHIPS OF SERUM LEPTIN CONCENTRATION WITH INSULIN, GLUCOSE, HbA1c LEVELS AND INSULIN RESISTANCE IN OVERWEIGHT POST-MENOPAUSAL DIABETIC WOMEN |
| Autores: |
Taghdir, Maryam; MS, Department of Nutrition and Biochemistry, School of Health, Tehran University of Medical Sciences, Tehran. Djazayeri, Abolghasem; PhD, Professor of Nutrition, Department of Nutrition and Biochemistry, School of Health, Tehran University of Medical Sciences, Tehran. Djalali, Mahmoud; PhD, Professor of Biochemistry, Department of Nutrition and Biochemistry, School of Health, Tehran University of Medical Sciences, Tehran. Eshraghian, Mohammadreza; PhD, Associate Professor, Department of Biostatistics, School of Health, Tehran University of Medical Sciences, Tehran. Rajab, Asadollah; MD, Endocrinologist, Iranian Diabetes Society, Tehran. Sadrzade Yegane, Haleh; MS, Instructor, Department of Nutrition and Biochemistry, School of Health, Tehran University of Medical Sciences, Tehran. Ashourpour, Mahkameh; MS, Department of Nutrition and Biochemistry, School of Health, Tehran University of Medical Sciences, Tehran. Sepandi, Mojtaba; MS, Instructor, Department of Epidemiology and Biostatistics, School of Health, Jondishapour University of Medical Sciences, Ahwaz. |
| Fecha: | 2010-11-30 |
| Publicador: | ARYA Atheroscler |
| Fuente: |
Ver documento |
| Tipo: | |
| Tema: | No aplica |
| Descripción: | Abstract BACKGROUND: Leptin, the product of the ob gene, could have a role in the pathogenesis of obesity and non-insulin dependent diabetes mellitus (NIDDM). The aim of this study was to investigate relationships between serum leptin concentration and insulin, glucose, HbA1c levels and insulin resistance in diabetic women. METHODS: We studied 45 diabetic women and 45 healthy women (controls) who aged 45-60 years and had BMI of 25-30 kg/m2. Serum leptin, insulin, HbA1c, fasting blood sugar and insulin resistance were determined in the two groups. RESULTS: There was a significant positive correlation between leptin and insulin (r = 0.295, P = 0.049) and insulin resistance (r = 0.329, P = 0.027) in controls but non-significant correlation between leptin and HbA1c and fasting blood sugar were observed in the two groups. CONCLUSION: This study did not document any significant relationship between serum leptin and insulin, glucose, HbA1c and insulin resistance in diabetic women. Keywords: Type 2 Diabetes Mellitus, Leptin, Insulin. |
| Idioma: | Inglés |
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