L
Título: LIVER-PROTECTIVE EFFECTS OF HYDROALCOHOLIC EXTRACT OF ALLIUM HIRTIFOLIUM BOISS. IN RATS WITH ALLOXAN-INDUCED DI-ABETES MELLITUS
Autores: Kazemi, Somayeh; Department of Biology, School of Sciences, The University of Isfahan and Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan
Asgary, Sedigheh; Isfahan Cardiovascular Research Center, Applied Physiology Research Center, Isfahan University of Medical Sciences, Isfahan
Moshtaghian, Jamal; Department of Biology, School of Sciences, The University of Isfahan, Isfahan
Rafieian, Mahmoud; Medicinal Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord
Adelnia, Azadeh; Department of Biology, School of Science, Isfahan Payam-e-Noor University, Isfahan
Shamsi, Fatemeh; Department of Biology, School of Science, Isfahan Payam-e-Noor University, Isfahan
Fecha: 2010-11-02
Publicador: ARYA Atheroscler
Fuente: Ver documento
Tipo:
Tema: No aplica
Descripción: BACKGROUND: Diabetes mellitus is one of the most common endocrine disorders accompanied with many metabolic syndromes. Use of herbal medicines has always been an option to treat a great number of diseases such as diabetes and its complications. In this study the liver-protective effects of hydroalcoholic extract of Allium hirtifolium on liver enzymes level in rats with alloxan-induced diabetes mellitus was investigated.    METHODS: Thirty five male rats were randomly divided into five groups of seven; group 1: nondiabetic control, group 2: diabetic control, group 3: diabetic treated with shallot extract (0.1 g/kg), group 4: diabetic rats treated with shallot extract (1 g/kg), and group 5: diabetic treated with glibenclamide (0.6 mg/kg). Using intraperitoneal (IP) injection of alloxan monohydrate, diabetes mellitus was induced in rats. Diabetic rats were treated with intraperitoneal injection for 4 weeks. At the end of the experimental period fasting blood samples were collected.    RESULTS: Statistical analysis of the data indicated that hydroalcoholic extract of shallot can significantly decrease serum contents of liver enzymes (ALP, AST, and ALT) in treated groups. In most cases, the effectiveness of the extract on reduction of these enzymes is more than glibenclamide.                 CONCLUSION: Antioxidant compounds in the extract may recover liver damages caused by free radicals in diabetic rats.
Idioma: Inglés
Artículos similares:
COMPARING THE EFFECTS OF LOVASTATIN AND CORNUS MAS FRUIT ON FIBRINOGEN LEVEL IN HYPERCHOLESTEROLEMIC RABBITS por Asgary, Sedigheh; Associate Professor of Pharmacognosy, Isfahan Cardiovascular Research Center, Applied Physiology Research Center, Isfahan University of Medical Sciences, Isfahan,Rafieian-Kopaei, Mahmoud; Professor of Pharmacology, Shahrekord Medicinal Plants Research Center, Shahrekord University of Medical Sciences, Sharekord,Adelnia, Azadeh; MSc, Animal Physiology, Department of Biology, University of Payam-Noor. Isfahan,Kazemi, Somayeh; MSc, Animal Physiology, Department of Biology, The University of Isfahan, Isfahan,Shamsi, Fatemeh; MSc, Animal Physiology, Department of Biology, University of Payam-Noor. Isfahan
DELAY AND ITS RELATED FACTORS IN SEEKING TREATMENT IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION por Taghaddosi, Mohsen; Department of Medical-Surgical Nursing, Kashan University of Medical Sciences, Kashan,Dianati, Mansour; Medical Student, Kashan University of Medical Sciences, Kashan,Fath Gharib Bidgoli, Javad; Department of Medical Technology, Kashan University of Medical Sciences, Kashan,Bahonaran, Javad; Department of Medical Technology, Kashan University of Medical Sciences, Kashan
THE RELATIONSHIP BETWEEN ANKLE-BRACHIAL INDEX AND NUM-BER OF INVOLVED CORONARIES IN PATIENTS WITH STABLE ANGINA por Sadeghi, Masoumeh; Associated Professor of Cardiology, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,,Tavasoli, AliAkbar; Associated Professor of Cardiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan,Roohafza, Hamidreza; Psychiatrist of Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Sarrafzadegan, Nizal; Professor of Cardiology, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan
PULMONIC VALVE ENDOCARDITIS WITH PULMONARY ARTERY ENDARTERITIS IN A YOUNG MAN WITH CONGENITAL VENTRAL SEPTAL DEFECT por Fazlinezhad, Afsoon; Associate Professor of Cardiology, Department of Echocardiography, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad,Fallah, Azadeh; Resident of Cardiology, Department of Cardiology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad,Esfahanizadeh, Jamil; Assistant Professor of Cardiac Surgery, Department of Cardiac Surgery, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad,
EFFECT OF HYDROGENATED, LIQUID AND GHEE OILS ON SERUM LI-PIDS PROFILE por Mohammadifard, Noushin; MSc, Department of Nutrition, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Nazem, Masoud; Associate Professor, Department of Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan,Naderi, Gholam-Ali; Associate Professor, Department of Basic Sciences, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Saghafian, Faezeh; BSc, Department of Nutrition, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Sajjadi, Firoozeh; BSc, Department of Nutrition, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Maghroon, Maryam; BSc, Department of Nutrition, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Bahonar, Ahmad; MD, MPH, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Alikhasi, Hasan; BSc, Department of Nutrition, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Nouri, Fatemeh; Biostatistics Unit, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan
EFFECT OF DIFFERENT PHYSICAL ACTIVITY TRAINING METHODS ON OVERWEIGHT ADOLESCENTS por Ghatrehsamani, Shohreh; Research Assistant, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Khavarian, Noushin; Research Assistant, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Beizaei, Maryam; Research Assistant, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Ramedan, Reza; Senior Expert, Isfahan Sport Training Organization, Isfahan,Poursafa, Parinaz; Senior Expert, Isfahan Sport Training Organization, Isfahan,Kelishadi, Roya; Associate Professor of Pediatrics, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan
THE ASSOCIATION OF GENERAL AND CENTRAL OBESITY WITH MA-JOR DIETARY PATTERNS IN ADULT WOMEN LIVING IN TEHRAN, IRAN por Rezazadeh, Arezoo; MSc, Department of Community Nutrition, School of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran,Rashidkhani, Bahram; PhD, Department of Community Nutrition, School of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran
EVALUATION OF LEPTIN AND ADIPONECTIN LEVELS IN PATIENTS WITH STABLE ANGINA PECTORIS por Mozafari, Masoud; Cardiology Resident, Isfahan University of Medical Sciences, Isfahan,Sadeghi, Masoumeh; Associate Professor of Cardiology, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,Sanei, Hamid; Associate Professor of Cardiology, Isfahan University of Medical Sciences, Isfahan,Ramezani, Mohammad Arash; Community Medicine Specialist, Isfahan Cardiovascular Research Center, Isfahan,Golabchi, Allahyar; Cardiology Resident, Isfahan University of Medical Sciences, Isfahan,Sarrafzadegan, Nizal; Professor of Cardiology, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences Isfahan
IS THERE ANY RELATIONSHIP BETWEEN C-REACTIVE PROTEIN LEV-EL AND COMPLEX CORONARY PLAQUES IN PATIENTS WITH UNSTABLE ANGINA? por Sadeghi, Masoumeh; Associate Professor, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan,,Pourmoghaddas, Masoud; Professor, Isfahan University of Medical Sciences, Isfahan,Tavasoli, Aliakbar; Associate Professor, Isfahan University of Medical Sciences, Isfahan,Roohafza, Hamidreza; Psychiatrist, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan
10 
RELATIONSHIP BETWEEN CAROTID INTIMA-MEDIA THICKNESS WITH SOME INFLAMMATORY BIOMARKERS, GHRELIN AND ADIPONECTIN IN IRANIANS WITH AND WITHOUT METABOLIC SYNDROME IN ISFAHAN COHORT STUDY por Hajmohammadi, Taiebeh; Resident of Cardiology, Isfahan University of Medical Sciences,Sadeghi, Masoumeh; Associate Professor of Cardiology, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences,Dashti, Masoumeh; Resident of Neurology, Isfahan University of Medical Sciences,Hashemi, Mohammad; Associate Professor of Cardiology, Isfahan University of Medical Sciences,Saadatnia, Mohammad; Associate Professor of Neurology, Isfahan University of Medical Sciences,Soghrati, Mojgan; General Practitoner, Medical Researcher,Talaei, Mohammad; Medical doctor, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences,Sarrafzadegan, Nizal; Professor of Cardiology, Head of Isfahan Cardiovascular Research Center, Isfahan