| Título: | Location of Sentinel Lymph Node in Gastric Cancer: A Modified, Painless And Noninvasive Approach |
| Autores: |
Su, Xin-hui Chen, Qiang Sun, Long Wu, Hua Pan, Wei-Ming Chen, Gui-bing Luo, Zuo-Ming Wang, Wei |
| Fecha: | 2010-03-30 |
| Publicador: | Chinese Journal of Cancer Research |
| Fuente: |
Ver documento |
| Tipo: | |
| Tema: | No aplica |
| Descripción: | Objective: The presence of lymph node metastases is an important factor in the prognosis of gastric cancer patient. Therefore, the precise identification of sentinel lymph nodes (SLN) in these patients is critical. In this work, we investigated the feasibility and preciseness by injection of 99mTc-sulfur colloid (SC) 2 hours before operation after general anesthesia, instead of one day before surgery. Methods: Thirty-one patients of gastric cancer diagnosed as T1−T3 were enrolled in this study. During operation, a SLN was defined as those containing 10 times more radioactivity than surrounding tissue with a hand-held gamma probe and removed. All the patients underwent radical gastrectomy with extended lymphadenectomy. All resected nodes were examined postoperatively by routine H&E stain and those negative SLNs were examined with further cytokeratin immunohistochemistical staining. Results: The incidence of metastasis was significantly higher in SLNs than in non-SLNs (x2=67.48, P |
| Idioma: | Inglés |