| Título: | Genotoxic effect of alkaloids |
| Autores: |
Henriques, Joao Antonio Pegas Moreno, Paulo Roberto Hrihorowitsch Von Poser, Gilsane Lino Querol, Carmen Boto Henriques, Amelia Teresinha |
| Fecha: |
2010-04-16 1991 |
| Publicador: | |
| Fuente: |
Ver documento |
| Tipo: |
Artigo de periódico Nacional |
| Tema: |
Alkaloíds Alcaloides : Genotoxicidade : Saccharomyces cerevisiae Alcalóides SOS-chromotest Saccharomyces cerevisiae Sos chromoteste Saccharomyces cerevisiae Mutation Genotoxicidade Recombination |
| Descripción: | Because of the increased use of alkaloids in general medical practice in recent years, it is of interest to determine genotoxic, mutagenic and recombinogenic response to different groups of alkaloids in prokaryotic and eucaryotic organisms. Reserpine, boldine and chelerythrine did not show genotoxicity response in the SOS-Chromotest whereas skimmianine showed genotoxícity in the presence of a metabolic activation mixture. Voacristine isolated from the leaves of Ervatamia coronaria shows in vivo cytostatic and mu tagenic effects in Saccharomyces cerevisiae hapioids cells. The Rauwolfia alkaloid (reserpine) was not able to induce reverse mutation and recombinational mitotic events (crossing-over and gene conversion) in yeast diploid strain XS2316. |
| Idioma: | Inglés |
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2 A vida em separado : estudo de um condomínio fechado de Porto Alegre por Quadros, Caroline Souza de | 7 |
3 | 8 O clítico acusativo na redação escolar por Dutra, Líria Romero |
4 "O passado está prenhe do futuro" : a escrita da história no Instituto Histórico e Geográfico do Rio Grande do Sul (1920-30) por Silveira, Daniela Oliveira | 9 Superfície de imagens : o tema do olhar em Borges e em Cortázar por Botelho, José Francisco Hillal Tavares de Junqueira |
5 | 10 |