| Título: | Studio comparativo H-MRS di indici di N-acetilaspartato ai centri semiovali umani |
| Autores: |
Rotondo, E. Bruschetta, P. Bramanti, P. Di Pasquale, M.R. |
| Fecha: | 2005-06-10 |
| Publicador: | Accademia Peloritana dei Pericolanti |
| Fuente: |
Ver documento |
| Tipo: |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed article Articolo valutato secondo i criteri della peer review |
| Tema: | |
| Descripción: | Standard INACS, Index of N-actyl-L-aspartate at centrum semiovale obtained by H-MRS, are compared to those of two Groups of volunteers. Group 1 was formed by 30 individuals (65-74 years old) with small cognition deficit a probably due to early AD (Alzheimer Disease). Mean INACS of Group 1 was lower than the standard (significance = 89,4%, t = 1.64). This suggest that INACS evaluation could help early AD diagnosis. Group 2 was formed by 15 individuals (45-59 years old) with structural damages due to outcomes of Transitory Ischemic Attacks (TIA) or Minor Strokes (MS). In spite of the evident neuronal/axonal degeneration, mean INACS of this Group do not show significative decrease. This could be interpreted on the basis of the presence in the glial cell of N-acetyl derivatives whose resonances overlap the N-acetyl-L-aspartate one masking its lack. |
| Idioma: | eng |