Título: | Synthesis of N-(morpholinomethyl) benzamides as moclobemide analogs |
Autores: |
Pessoa, H. Astudillo, C. I. Araya Maturana, R. |
Fecha: |
2011-06-02 2011-06-02 2002 |
Publicador: | MARCEL DEKKER INC |
Fuente: |
Ver documento |
Tipo: | Artículo de Revista |
Tema: |
Moclobemide analogs Synthesis Monoamine oxidase (MAO) |
Descripción: |
Artículo de publicación ISI Syntheses of new morpholinomethylbenzamides 6 bearing both electron-withdrawing and electron-releasing groups at the aromatic ring are described. The strategy involved synthesis of hippuric acid ethyl esters 3, their hydrolysis to hippuric acids 4, subsequent oxidative decarboxylation to acetate 5 and morpholine addition to provide 6. |
Idioma: | Inglés |