| Título: | Protective Effect of Vitamins C and E on Malathion-Induced Nephrotoxicity in Male Rats |
| Autores: |
Fatma GOKCE UZUN Yusuf KALENDER |
| Fecha: | 2011-04-05 |
| Publicador: | GAZI UNIVERSITY JOURNAL OF SCIENCE |
| Fuente: |
Ver documento |
| Tipo: | Peer-reviewed Article |
| Tema: |
Histology,Toxicology Organophosphate insecticide, Malathion, Nephrotoxicity, Vitamin C, Vitamin E |
| Descripción: | The male Wistar rats were given malathion and/or vitamin C+vitamin E daily via gavage for 4 weeks. When malathion-, vitamins C+E plus malathion-treated groups were compared to control, body and kidney weights decreased; serum urea, uric acid and creatinine levels increased significantly. Vitamins C+E plus malathion-treated group was compared to malathion-treated group there were statistically decrease in the serum urea level, while no significant changes were observed in other parameters. Light microscopic investigations revealed that both the malathion- and vitamins C+E plus malathion-treated groups exhibited histopathological changes in kidney. It appears that vitamins C and E didn’t ameliorate malathion-induce nephrotoxicity.Keywords: Organophosphate insecticide, Malathion, Nephrotoxicity, Vitamin C, Vitamin E. |
| Idioma: | Inglés |