Título: | Biclustering Algorithm for Embryonic Tumor Gene Expression Dataset: LAS Algorithm |
Autores: |
Alavi Majd, Hamid; Biostatistics Department, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran Shahsavari, Soodeh; Biostatistics Department, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran Khodakarim, Soheila; School of Public Health, Shahid Beheshti University of Medical Science, Tehran Tabatabaei, Seyyed Mohammad; Medical Informatics Department, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran Nobakht Motlagh Ghochani, Bi bi Fatemeh; Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran |
Fecha: | 2013-03-02 |
Publicador: | Journal of Paramedical Sciences |
Fuente: |
Ver documento |
Tipo: |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
Tema: |
Biclustering algorithm; LAS procedure; Gene expression data Biclustering Algorithm for Embryonic Tumor Gene Expression Dataset: LAS Algorithm |
Descripción: | An important step in considering of gene expression data is obtained groups of genes that have similarity patterns. Biclustering methods was recently introduced for discovering subsets of genes that have coherent values across a subset of conditions. The LAS algorithm relies on a heuristic randomized search to find biclusters. In this paper, we introduce biclustering LAS algorithm and then apply this procedure for real value gene expression data. In this study after normalized data, LAS performed. 31 biclusters were discovered that 26 of them were for positive gene expression values and others were for negative. Biological validity for LAS procedure in biological process, in molecular function and in cellular component were 77.96% , 62.28% and 74.39% respictively. The result of biological validation of LAS algorithm in this study had shown LAS algorithm effectively convenient in discovering good biclusters. |
Idioma: | Inglés |
1 Investigation of genetic association between PRODH gene and schizophrenia in Iranian population por Rahman zadeh, Saeid; Department of biology , Faculty of sciences , Islamic azad university, Science & Research campus , Tehran,Shahbaz Mohammadi, Hamid; Department of Biochemistry Pasteur Institute of IRAN,karimipour, Morteza; Molecular Medicine Group, Biotechnology research Centre, Pasteur Institute of IRAN, Tehran, IRAN,Heidari keshel, Saeed; proteomics research center, Shahid Beheshti University of Medical Sciences, Tehran, IRAN | 6 Knowledge-based potentials in protein fold recognition por Mirzaie, Mehdi; Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran,Sadeghi, Mehdi; National Institute of Genetic Engineering and Biotechnology, Tehran; School of Computer Science, Institute for Research in Fundamental Sciences (IPM), Tehran |
2 Valproate Effects on Chemophysical Properties of Human Serum Albumin por Zamanian-Azodi, Mona; Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran,Akbari, Mohammad Esmaeil; Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran,Khademi, Hamidreza; Dept. of Biology, Science and Research Branch, Islamic Azad University, Tehran | 7 Investigation of heat stress in workplace for different work groups according to ISO 7243 standard in Mehr Petrochemical Complex, Assaluyeh, Iran por Hemmatjo, Rasool; Occupational Health Faculty, Bousher University of Medical Sciences, Bushehr,Zare, Sajad; Department of Occu¬pational Health, School of Public health, Tehran University of Medical Sciences, Tehran,Babaei Heydarabadi, Akbar; Department of Public Health, Student`s committee research, Faculty of Health, Shahid Beheshti University of Medical Sciences, Tehran,Hajivandi, Abdollah; Occupational Health Faculty, Bushehr University of Medical Sciences, Bushehr |
3 The effect of epidural morphine sponge in postoperative pain control after Microdiscectomy por Movasaghi, Reza; Imam Reza Teaching Hospital, Tabriz University of Medical Sciences, Tabriz,Salehpour, Firooz; Imam Reza Teaching Hospital, Tabriz University of Medical Sciences, Tabriz,Ahmadvand, Ali; Imam Reza Teaching Hospital, Tabriz University of Medical Sciences, Tabriz,Agha-Mohammadi, Davood; Imam Reza Teaching Hospital, Tabriz University of Medical Sciences, Tabriz,Dorosty, Abbas Ali; Imam Reza Teaching Hospital, Tabriz University of Medical Sciences, Tabriz,Vafaee, Reza; Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran | 8 Antinociceptive & anti-inflammatory effects of Berberis vulgaris L. root's hydroalcoholic extract and determination of it’s possible antinociceptive mechanism in male mice por Mohebali, Shahrdad; Department of Biology, Payamenoor University, PO BOX19395-3697Tehran,Nasri, Sima; Department of Biology, Payamenoor University, PO BOX19395-3697Tehran,Kamalinejhad, Mohammad; 3Department of Pharmacognosy, Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran,Noori, Azam Sadat; 4Department of Biology, Faculty of Biological Sciences, Tarbiat Modares University,Tehran |
4 Evaluation of Pluripotency Gene Expression in Mouse Embryonic Stem Cell Cultured on the Human Feeder Layer por Heidari -Keshel, Saeed; Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of medical Science, Tehran; Stem cell preparation unit, Farabi hospital, Faculty of medical Science, Tehran,Soleimani, Masoud; Department of hematology, Faculty of medical Science, Tarbiat Modares University,khoshzaban, Ahad; Stem cell preparation unit, Farabi hospital, Faculty of medical Science, Tehran,Ebrahimi, Maryam; Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of medical Science, Tehran; Stem cell preparation unit, Farabi hospital, Faculty of medical Science, Tehran,Heidari, Mohammad Hossein; Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of medical Science, Tehran | 9 The role of medical sciences journals in the health promotion por Rahmati Roodsar, Mohammad; Research Vice Chancellor of Shahid Beheshti University of Medical Sciences, Tehran |
5 Analysis of longitudinal binary outcomes in clinical trials with low percentage of missing values por Akbarzadeh Baghban, Alireza; Department of Basic Sciences, School of Rehabilitation Sciences, Shahid Beheshti University of Medical Sciences, Tehran,Ghasemi, Erfan; Department of Biostatistics, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran,Zayeri, Farid; Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran,Asgary, Saeed; Iranian Center of Endodontic Research, Dental Research Center, Shahid Beheshti University of Medical Sciences, Tehran,Namdari, Mahshid; Department of Biostatistics, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran | 10 Long-term exposure to low frequency electro-magnetic fields of 50- and 217-Hz leads to learning and memory deficits in mice por Nooshinfar, Elaheh; Cancer Research Center, Shahid Beheshti university of medical sciences, Tehran,Rezaei-Tavirani, Mostafa; Proteomics Research Center, Faculty of paramedical sciences, Shahid Beheshti university of medical sciences, Tehran,Khodakarim, Soheila; Proteomics Research Center, Faculty of paramedical sciences, Shahid Beheshti university of medical sciences, Tehran |