| Título: | Intravitreal Triamcinolone for Acute Branch Retinal Vein Occlusion: a Randomized Clinical Trial |
| Autores: |
Alireza Ramezani; Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran Morteza Entezari Siamak Moradian Shohreh Kadkhodaei Homa Tabatabaei Babak Dehsarvi Mohammad Fatehi Mehdi Yaseri |
| Fecha: | 2011-05-21 |
| Publicador: | Ophthalmic Research Center |
| Fuente: |
Ver documento |
| Tipo: | |
| Tema: | No aplica |
| Descripción: | PURPOSE: To evaluate the therapeutic effect of intravitreal triamcinolone (IVT) injection for recent branch retinal vein occlusion (BRVO). METHODS: In a randomized controlled clinical trial, 30 phakic eyes with recent (less than 10 weeks' duration) BRVO were assigned to two groups. The treatment group (16 eyes) received 4 mg IVT and the control group (14 eyes) received subconjunctival sham injections. Changes in visual acuity (VA) were the main outcome measure. RESULTS: VA and central macular thickness (CMT) changes were not significantly different between the study groups at any time point. Within group analysis showed significant VA improvement from baseline in the IVT group up to three months (P < 0.05); the amount of this change was 0.53 ± 0.46, 0.37 ± 0.50, 0.46 ± 0.50, and 0.29 ± 0.45 logMAR at 1, 2, 3, and 4 months, respectively. Corresponding VA improvements in the control group were 0.20 ± 0.37, 0.11 ± 0.46, 0.25 ± 0.58, and 0.05 ± 0.50 logMAR (all P values > 0.05). Significant reduction in CMT was noticed only in the treatment group (172 ± 202 microns, P = 0.029) and at 4 months. Ocular hypertension occurred in 4 (25%) and 2 (14.3%) eyes in the IVT and control groups, respectively. CONCLUSION: A single IVT injection had a non-significant beneficial effect on VA and CMT in acute BRVO as compared to the natural history of the condition. The 3-month deferred treatment protocol advocated by the Branch Vein Occlusion Study Group may be a safer option than IVT injection considering its potential side effects. |
| Idioma: | Inglés |
1 Short-term Results of Two Treatment Regimens in Ocular Toxoplasmosis: Trimethoprim/Sulfamethoxazole versus Pyrimethamine and Sulfadiazine por Mohammad-Mehdi Sadoughi; Shahid Beheshti University, M.C.,Masoud Soheilian; Shahid Beheshti University, M.C.,Mohammad-Hossein Dehghan; Shahid Beheshti University, M.C.,Hassan Behboudi; Gilan University of Medical Sciences, Rasht,Arash Anisian; Shahid Beheshti University, M.C.,Shahin Yazdani; Shahid Beheshti University, M.C. | 6 Visual Function following Treatment of Optic Neuritis por Majid Abrishami; Mashhad University of Medical Sciences,Mir-Naghi Moosavi; Mashhad University of Medical Sciences,Abbas Azimi-Khorasani; Mashhad University of Medical Sciences,Azardokht Vazifeshenas; Mashhad University of Medical Sciences |
2 Outcomes of Surgical Treatment for Retinal Detachment Resulting from Macular Hole in Highly Myopic Eyes por Amir-Khosro Ghaseminejad; Kerman University of Medical Sciences, Kerman,Masoud Soheilian; Shahid Beheshti University, M.C.,Arash Anisian; Shahid Beheshti University, M.C.,Hamid Ahmadieh; Shahid Beheshti University, M.C.,Mohsen Azarmina; Shahid Beheshti University, M.C. | 7 Changing Concepts in the Surgical Repair of Primary Retinal Detachment: The Odyssey of a Leaking Break (part 1) por Ingrid Kreissig; Department of Ophthalmology, Clinical Faculty, Mannheim University, Heidelberg |
3 Subtenon Carboplatin in the Management of Intraocular Retinoblastoma por Reza Karkhaneh; Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran,Naseh Mohammadi; Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran,Hormoz Chams; Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran,Parvaneh Vosough; Iran University of Medical Sciences, Tehran,Mansour Rezaei; Iran University of Medical Sciences, Tehran,Naser Valaei; Shahid Beheshti University, M.C. | 8 Ocular Complications of Brucellosis: a Case Report por Ali-Reza Lashay; Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran,Mohammad-Reza Manaviat; Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran,Reza Azimi; Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran,Mohammad Riazi; Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran |
4 Prophylactic Effects of Mitomycin-C on Regression and Haze Formation in Photorefractive Keratectomy por Hassan Hashemi; Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran,Mohammad-Reza Taheri; Noor Eye Clinic, Tehran,Akbar Fotouhi; Health Faculty, Tehran University of Medical Sciences, Tehran | 9 Early Results of Autologous Cultivated Limbal Stem Cell Transplantation in Total Limbal Stem Cell Deficiency por Mohammad Ali Javadi; Shahid Beheshti University, M.C.,Bahram Einollahi; Shahid Beheshti University, M.C.,Alireza Baradaran Rafiei; Shahid Beheshti University, M.C.,Hossein Baharvand; Rooyan Research Center, Tehran, Iran,Marzieh Ebrahimi; Rooyan Research Center, Tehran, Iran,Nasrin Rafati; Shahid Beheshti University, M.C.,Mojgan Rezaei Kanavi; Shahid Beheshti University, M.C. |
5 Etiology of Oculomotor Nerve Paralysis por Abdul-Reza Tabassi; Tehran University of Medical Sciences, Tehran,Ali-Reza Dehghani; Isfahan University of Medical Sciences, Isfahan,Hamid Mosayebi; Tehran University of Medical Sciences, Tehran | 10 Amniotic Membrane Transplantation for Congenital Distichiasis por Hossein Saloor; Shahid Beheshti University, M.C.,Maryam Aletaha; Shahid Beheshti University, M.C. |