| Título: | Possibility of Thyroidism Diagnosis by Laser Induced Breakdown Spectroscopy of Human Fingernail |
| Autores: |
Bahreini, Maryam; Laser and Plasma Research Institute, Shahid Beheshti University, G. C., Evin, Tehran, 1983963113, Iran Tavassoli, Seyed Hassan; Laser and Plasma Research Institute, Shahid Beheshti University, G. C., Evin, Tehran, 1983963113, Iran |
| Fecha: | 2012-07-30 |
| Publicador: | Laser Application in Medical Sciences Research Center |
| Fuente: |
Ver documento |
| Tipo: |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| Tema: | discriminant analysis; thyroid diseases; hypothyroidism; fingernail |
| Descripción: | INTRODUCTION: A modern technique for elemental analysis of biological samples is laser induced breakdown spectroscopy (LIBS). This technique is based on emission of excited atoms, ions, and molecules in plasma produced by focusing a high power laser pulses on sample surface. Because of several advantages of LIBS including little or no sample preparation; minimally invasive; fast analysis time and very easy to use, in this study, this method was used for investigating the mineral content of fingernails. As the trace element of nail can be changed by several pathological, physiological, and environmental factors, we analyze the human fingernails to evaluate the possibility of thyroidism diagnosis.METHODS: A Q-switched Neodymium-Doped Yttrium Aluminium Garnet (Nd:YAG) laser operating at wavelength of 1064 nm, pulse energy of 50 mJ/pulse, repetition rate of 10 Hz and pulse duration of 6 ns was used in this analysis. Measurements were done on 28 fingernails belonging to 5 hypothyroid, 2 hyperthyroid and 21 normal subjects. For classification of samples into different groups based on thyroid status, a discriminant function analysis (DFA) was used to discriminate among normal and thyroidism groups.RESULTS: The elements detected in fingernails with the present system were: Al, C, Ca, Fe, H, K, Mg, N, Na, O, Si, Sr, Ti as well as CN molecule. Classification in two groups of normal and patient subjects and also in three groups of normal, hyperthyroid and hypothyroid subjects shows that 100% of original grouped cases were correctly classified. So, efficient discrimination among these groups is demonstrated.CONCLUSION: It is shown that laser-induced breakdown spectroscopy (LIBS) could be a possible technique for the analysis of nail and therefore identification of health problems. |
| Idioma: | Inglés |
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3 Low Level Laser Therapy in Management of Chemotherapy-Induced Oral Mucositis: Prophylaxis or Treatment? por Esmaeeli Djavid, Gholamreza; Photobiostimulation Research Group, Iranian Center for Medical Laser, Academic Center for Education, Culture, and Research (ACECR), Tehran, Iran,Emami, Amirhossein; Assistant Professor of Hematology and Oncology, Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran,Ataie-Fashtami, Leila; Assistant Professor of Dermatology, Iranian Center for Medical Laser, Academic Center for Education, Culture, and Research (ACECR), Tehran, Iran,Safaeinodehi, Seyed reza; Assistant Professor of Hematology and Oncology, Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran,Merikh-Baiat, Farzad; Researcher, Tehran University of Medical Sciences, Tehran, Iran,Fateh, Mohsen; Photobiostimulation Research Group, Iranian Center for Medical Laser, Academic Center for Education, Culture, and Research (ACECR), Tehran, Iran,Zand, Nasrin; Assistant Professor of Dermatology, Iranian Center for Medical Laser, Academic Center for Education, Culture, and Research (ACECR), Tehran, Iran | 8 Effects of Erbium-Doped: Yttrium Aluminum Garnet (Er: YAG) Laser on Bacteremia due to Scaling and Root Planing por Komatsu, Yasutaka; Niigata University,Morozumi, Toshiya; Niigata University,Abe, Daisuke; Niigata University,Okada, Moe; Niigata University,Nakasone, Naohiro; Niigata University,Okuda, Kazuhiro; Niigata University,Yoshie, Hiromasa; Niigata University |
4 Using Diode Laser for Soft Tissue Incision of Oral Cavity por Amid, Reza; Dental Research Center, Department of Periodontics, Shahid Beheshti University of Medical Sciences, Tehran, Iran,Kadkhodazadeh, Mahdi; Dental Research Center, Department of Periodontics, Shahid Beheshti University of Medical Sciences, Tehran, Iran,Talebi Ardakani, Mohammadreza; Dental Research Center, Department of Periodontics, Shahid Beheshti University of Medical Sciences, Tehran, Iran,Hemmatzadeh, Somayeh; School of Dentistry, Department of Periodontics, Shahid Beheshti University of Medical Sciences, Tehran, Iran,Refoua, Soheil; School of Dentistry, Department of Periodontics, Shahid Beheshti University of Medical Sciences, Tehran, Iran,Iranparvar, Parastoo; School of Dentistry, Department of Periodontics, Shahid Beheshti University of Medical Sciences, Tehran, Iran,Shahi, Anahita; School of Dentistry, Department of Periodontics, Shahid Beheshti University of Medical Sciences, Tehran, Iran | 9 Micromorphological Evaluation of Dentin Treated with Different Desensitizing Agents por osmari, deise; Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil.,ferreira, ana carolina de oliveira; Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil.,bello, Mariana De Carlo; Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil.,susin, alexandre henrique; Department of Dentistry, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil,aranha, ana cecília correia; Department of Dentistry at the college of Dentistry of São Paulo, University of São Paulo (USP), São Paulo, SP, Brazil.,marquezan, marcela; Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil.,da silveira, bruno lopes; Department of Dentistry, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil |
5 Temperature Distribution Simulation of the Human Eye Exposed to Laser Radiation por Mirnezami, Seyyed Abbas; Iranian national center of laser science and technology,Rajaei Jafarabadi, Mahdi; Iranian national center of laser science and technology,Abrishami, Maryam; Iranian national center of laser science and technology | 10 Treatment of Great Saphenous Vein Insufficiency by Endovenous Laser Therapy: Clinical Description and Short Term Follow up of 20 Iranian Patients por Mozafar, Mohammad; Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.,Haghighatkhah, Hamidreza; Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.,Sanei Taheri, Morteza; Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.,Atqiaee, Khashayar; Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.,Tabatabaei, Seid Ali; Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.,Tadayon, Niki; Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. |