| Título: | Prophylactic feeding tubes for patients with locally advanced head-and-neck cancer undergoing combined chemotherapy and radiotherapy—systematic review and recommendations for clinical practice |
| Autores: |
Orphanidou, C.; BC Cancer Agency Biggs, K.; Juravinski Cancer Centre Johnston, M.E.; Technical and Methodological Consultant Wright, J.R.; Juravinski Cancer Centre Bowman, A.; BC Cancer Agency Hotte, S.J.; Juravinski Cancer Centre Esau, A.; Tom Baker Cancer Centre Myers, C.; Cancer Care Manitoba Blunt, V.; University Health Network (Toronto General Hospital) Lafleur, M.; Juravinski Cancer Centre Sheehan, B.; BC Cancer Agency Griffin, M.A.; Dr. H. Bliss Murphy Cancer Centre |
| Fecha: | 2011-08-04 |
| Publicador: | Multimed Inc. |
| Fuente: |
Ver documento |
| Tipo: |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| Tema: | Practice guideline; systematic review; tube feeding; chemoradiation; head-and-neck cancer |
| Descripción: | GoalsThis work aimed to determine the benefits and risks of prophylactic feeding tubes for adult patients with squamous cell carcinoma of the head and neck who receive combined chemotherapy and radiotherapy with curative intent and to make recommendations on the use of prophylactic feeding tubes and the provision of adequate nutrition to this patient population. MethodsA national multidisciplinary panel conducted a systematic review of the evidence and formulated recommendations to guide clinical decision-making. The draft evidence summary and recommendations were distributed to clinicians across Canada for their input.Main ResultsNo randomized controlled trials have directly addressed this question. Evidence from studies in the target population was limited to seven descriptive studies: two with control groups (one prospective, one retrospective) and five without control groups. Results from ten controlled studies in patients treated with radiotherapy alone were also reviewed. ConclusionsThe available evidence was insufficient to draw definitive conclusions about the effectiveness of prophylactic feeding tubes in the target patient population or to support an evidence-based practice guideline. After review of the evidence, of guidelines from other groups, and of current clinical practice in Canada, the multidisciplinary panel made consensus-based recommendations regarding comprehensive interdisciplinary clinical care before, during, and after cancer treatment. The recommendations are based on the expert opinion of the panel members and on their understanding of best clinical practice. |
| Idioma: | Inglés |
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