| Título: | The roads to and from the RNA world |
| Autores: |
Dworkin, JP Lazcano Araujo Reyes, Antonio Eusebio Miller, SL |
| Fecha: |
20130312T14:38:30Z 20130312T14:38:30Z 2003 |
| Publicador: | Facultad de Ciencias - UNAM |
| Fuente: |
 |
| Tipo: | Artículo de investigación |
| Tema: |
Biology Mathematical & Computational Biology RNA world ribose deoxyribose prebiotic evolution preRNA world |
| Descripción: | The historical existence of the RNA world, in which early life used RNA for both genetic information and catalytic ability, is widely accepted. However, there has been little discussion of whether protein synthesis arose before DNA or what preceded the RNA world (i.e. the preRNA world). We outline arguments of what route life may have taken out of the RNA world: whether DNA or protein followed. Metabolic arguments favor the possibility that RNA genomes preceded the use of DNA as the informational macromolecule. However, the opposite can also be argued based on the enhanced stability, reactivity, and solubility of 2deoxyribose as compared to ribose. The possibility that DNA may have come before RNA is discussed, although it is a less parsimonious explanation than DNA following RNA. (C) 2003 Elsevier Science Ltd. All rights reserved. |
| Idioma: | Inglés |