| Título: | Efficacy of analgesic effect of low dose intrathecal clonidine as adjuvant to bupivacaine in urogenital surgeries: study in a Kashmiri population |
| Autores: |
Shah, Zahoor Ahmad; Assistant Professor, Dept. of Anesthesiology & Critical Care, SKIMS, Srinagar, Jammu & Kashmir Kundal, Raksha; Resident, Dept. of Anesthesiology & Critical Care, SKIMS, Srinagar, Jammu & Kashmir Gupta, Arun Kumar; Assistant Professor, Dept. of Anesthesiology & Critical Care, SKIMS, Srinagar, Jammu & Kashmir Malla, Mohd Sadiq; Senior Resident, Dept. of Anesthesiology & Critical Care, SKIMS, Srinagar, Jammu & Kashmir Zahoor, Faisal; Resident5, Dept. of Emergency Medicine, Apollo Hospital, New Delhi Kundal, Vijay; Senior Resident, Dept. of Paediatric Surgery, SMS Hospital, Jaipur Kirmani, Sameena Ashraf; Resident, Dept. of Anesthesiology & Critical Care, SKIMS, Srinagar, Jammu & Kashmir Qazi, Shigufta; Professor & Head, Dept. of Anesthesiology & Critical Care, SKIMS, Srinagar, Jammu & Kashmir |
| Fecha: | 2012-04-21 |
| Publicador: | Sri Lankan journal of Anaesthesiology |
| Fuente: |
 |
| Tipo: |
info:eu-repo/semantics/article Peer-Reviewed Item info:eu-repo/semantics/publishedVersion |
| Tema: |
Anaesthesiology Bupivacaine; Clonidine; intrathecal |
| Descripción: | Background: Previous studies have shown that clonidine given intrathecally in higher doses cause side effects. In this study, we used low dose clonidine intrathecally (1 μg /kg) as adjuvant to bupivacaine to study efficacy of analgesia and side effects.Method: 60 patients were randomly divided into two groups of 30 patients each. They were aged 20 to 60 years, of ASA Class I and II undergoing genitourinary surgeries. The clonidine group (A) received 1 μg/kg clonidine in addition to bupivacaine 12.5mg (0.5%) and control group (B) received an identical volume of saline mixed with 12.5mg (0.5%) bupivacaine. Efficacy of spinal analgesia was compared between these two groups.Results: Duration of analgesia, motor block, highest level of sensory block and time taken for regression of sensory analgesia by two segments was more in the clonidine group. There was a reduction in heart rate and systolic blood pressure which was statistically insignificant. Side effects like nausea and sedation were insignificant.Conclusion: Addition of low dose clonidine (1μg/kg) to bupivacaine increases the duration of spinal analgesia as compared to bupivacaine alone with clinically insignificant influence on haemodynamic parameters and level of sedation.DOI: http://dx.doi.org/10.4038/slja.v20i1.3072 Sri Lankan Journal of Anaesthesiology 20(1): 49-52 (2012) |
| Idioma: | Inglés |
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